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Tuesday, November 10, 2009

HIV and Hepatitis B or C

filed under: HIV hepatitis B C treatment BHIVA guidelines

BHIVA has written new guidelines for the management of co-infection with HIV and hepatitis B or C and want people's comments. These guidelines replace the existing separate guidelines for HIV and Hepatitis B, and HIV and Hepatitis C. You can make your comments at the BHIVA website


These 2009 guidelines incorporate all new relevant information since the previous versions in 2005.

For 2009 we have decided to amalgamate the two guides for hepatitis coinfection into a single document. This avoids duplication, because general treatment for chronic liver disease is similar for both.


The translation of study data into clinical practice is often difficult, even with the best possible evidence, because of differences in factors such as trial design and inclusion criteria. Recommendations based upon expert opinion have the weakest evidence but provide an important reason for writing the guidelines – to produce a consensual opinion about current practice. The Writing Group seeks to provide guidelines that optimize treatment and management, but this needs to be tailored to fit the person - the draft is not suggesting a fixed standard for all.



Changes
The major changes/amendments include:

* More discussion on hepatitis screening and prevention;
* Clarification on the role of liver biopsy and non-invasive liver fibrosis assessment;
* More emphasis on screening for delta virus;
* More discussion on end-stage liver disease management and HCC screening;
* Molecular diagnostic tests used for the diagnosis and management of Hepatitis B and Hepatitis C;
* Revised CD4-based guidance on the management of chronic Hepatitis B;
* Management of acute Hepatitis B;
* Revised guidance on the management of chronic HCV, including ART interactions;
* Management of acute Hepatitis C
* Management of treatment non-responders and relapsers in both chronic Hepatitis B and C.



The consultation deadline is 5 June

BHIVA consultation page

Managing Coinfection with HIV and Hep B and C download the pdf

Online feedback form

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